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BMCBI
2008
13 years 7 months ago
2008
Background: Population structure is an important cause leading to inconsistent results in population-based association studies (PBAS) of human diseases. Various statistical method...
BMCBI
2008
13 years 7 months ago
2008
Background: Choosing the appropriate sample size is an important step in the design of a microarray experiment, and recently methods have been proposed that estimate sample sizes ...
BMCBI
2008
13 years 7 months ago
2008
Background: The Clinical E-Science Framework (CLEF) project has built a system to extract clinically significant information from the textual component of medical records in order...
BMCBI
2008
13 years 7 months ago
2008
Background: Single Nucleotide Polymorphisms (SNPs) are the most abundant form of genomic variation and can cause phenotypic differences between individuals, including diseases. Ba...
BMCBI
2008
13 years 7 months ago
2008
In studies that use DNA arrays to assess changes in gene expression, it is preferable to measure the significance of treatment effects on a group of genes from a pathway or functi...