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BMCBI
2008
114views more  BMCBI 2008»
13 years 8 months ago
Indel PDB: A database of structural insertions and deletions derived from sequence alignments of closely related proteins
Background: Insertions and deletions (indels) represent a common type of sequence variations, which are less studied and pose many important biological questions. Recent research ...
Michael Hsing, Artem Cherkasov
BMCBI
2008
129views more  BMCBI 2008»
13 years 8 months ago
An analytic and systematic framework for estimating metabolic flux ratios from 13C tracer experiments
Background: Metabolic fluxes provide invaluable insight on the integrated response of a cell to environmental stimuli or genetic modifications. Current computational methods for e...
Ari Rantanen, Juho Rousu, Paula Jouhten, Nicola Za...
BMCBI
2008
83views more  BMCBI 2008»
13 years 8 months ago
Terminologies for text-mining; an experiment in the lipoprotein metabolism domain
Background: The engineering of ontologies, especially with a view to a text-mining use, is still a new research field. There does not yet exist a well-defined theory and technolog...
Dimitra Alexopoulou, Thomas Wächter, Laura Pi...
BMCBI
2008
124views more  BMCBI 2008»
13 years 8 months ago
Ontology-based, Tissue MicroArray oriented, image centered tissue bank
Background: Tissue MicroArray technique is becoming increasingly important in pathology for the validation of experimental data from transcriptomic analysis. This approach produce...
Federica Viti, Ivan Merelli, Andrea Caprera, Barba...
BMCBI
2008
135views more  BMCBI 2008»
13 years 8 months ago
Ab-origin: an enhanced tool to identify the sourcing gene segments in germline for rearranged antibodies
Background: In the adaptive immune system, variable regions of immunoglobulin (IG) are encoded by random recombination of variable (V), diversity (D), and joining (J) gene segment...
Xiaojing Wang, Di Wu, SiYuan Zheng, Jing Sun, Lin ...
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