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    BMCBI
    2006
    131views more  BMCBI 2006»
    Statistical modeling of biomedical corpora: mining the Caenorhabditis Genetic Center Bibliography for genes related to life span
    13 years 9 months ago
    Statistical modeling of biomedical corpora: mining the Caenorhabditis Genetic Center Bibliography for genes related to life span
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    Background: The statistical modeling of biomedical corpora could yield integrated, coarse-to-fine views of biological phenomena that complement discoveries made from analysis of m...
    David M. Blei, K. Franks, Michael I. Jordan, I. Sa...
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    BMCBI
    2006
    82views more  BMCBI 2006»
    Selection of antisense oligonucleotides based on multiple predicted target mRNA structures
    13 years 9 months ago
    Selection of antisense oligonucleotides based on multiple predicted target mRNA structures
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    Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...
    Xiaochen Bo, Shaoke Lou, Daochun Sun, Wenjie Shu, ...
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    BMCBI
    2006
    130views more  BMCBI 2006»
    CARMA: A platform for analyzing microarray datasets that incorporate replicate measures
    13 years 9 months ago
    CARMA: A platform for analyzing microarray datasets that incorporate replicate measures
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    Background: The incorporation of statistical models that account for experimental variability provides a necessary framework for the interpretation of microarray data. A robust ex...
    Kevin A. Greer, Matthew R. McReynolds, Heddwen L. ...
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    BMCBI
    2006
    148views more  BMCBI 2006»
    Exploiting the full power of temporal gene expression profiling through a new statistical test: Application to the analysis of m
    13 years 9 months ago
    Exploiting the full power of temporal gene expression profiling through a new statistical test: Application to the analysis of m
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    Background: The identification of biologically interesting genes in a temporal expression profiling dataset is challenging and complicated by high levels of experimental noise. Mo...
    Veronica Vinciotti, Xiaohui Liu, Rolf Turk, Emile ...
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    BMCBI
    2006
    102views more  BMCBI 2006»
    Microarray analysis distinguishes differential gene expression patterns from large and small colony Thymidine kinase mutants of
    13 years 9 months ago
    Microarray analysis distinguishes differential gene expression patterns from large and small colony Thymidine kinase mutants of
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    Background: The Thymidine kinase (Tk) mutants generated from the widely used L5178Y mouse lymphoma assay fall into two categories, small colony and large colony. Cells from the la...
    Tao Han, Jianyong Wang, Weida Tong, Martha M. Moor...
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