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BMCBI
2008
114views more  BMCBI 2008»
13 years 7 months ago
WSPMaker: a web tool for calculating selection pressure in proteins and domains using window-sliding
Background: In the study of adaptive evolution, it is important to detect the protein coding sites where natural selection is acting. In general, the ratio of the rate of non-syno...
Yong Seok Lee, Tae-Hyung Kim, Tae-Wook Kang, Won-H...
BMCBI
2005
169views more  BMCBI 2005»
13 years 7 months ago
Genetic interaction motif finding by expectation maximization - a novel statistical model for inferring gene modules from synthe
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Yan Qi 0003, Ping Ye, Joel S. Bader
BMCBI
2005
132views more  BMCBI 2005»
13 years 7 months ago
Correlation and prediction of gene expression level from amino acid and dipeptide composition of its protein
Background: A large number of papers have been published on analysis of microarray data with particular emphasis on normalization of data, detection of differentially expressed ge...
Gajendra P. S. Raghava, Joon H. Han
BMCBI
2005
253views more  BMCBI 2005»
13 years 7 months ago
The Use of Edge-Betweenness Clustering to Investigate Biological Function in Protein Interaction Networks
Background: This paper describes an automated method for finding clusters of interconnected proteins in protein interaction networks and retrieving protein annotations associated ...
Ruth Dunn, Frank Dudbridge, Christopher M. Sanders...
BMCBI
2006
92views more  BMCBI 2006»
13 years 7 months ago
Similarity-based gene detection: using COGs to find evolutionarily-conserved ORFs
Background: Experimental verification of gene products has not kept pace with the rapid growth of microbial sequence information. However, existing annotations of gene locations c...
Bradford C. Powell, Clyde A. Hutchison III