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BMCBI
2010
126views more  BMCBI 2010»
13 years 5 months ago
PETALS: Proteomic Evaluation and Topological Analysis of a mutated Locus' Signaling
Background: Colon cancer is driven by mutations in a number of genes, the most notorious of which is Apc. Though much of Apc's signaling has been mechanistically identified o...
Gürkan Bebek, Vishal Patel, Mark R. Chance
BMCBI
2010
144views more  BMCBI 2010»
13 years 3 months ago
Optimizing Transformations for Automated, High Throughput Analysis of Flow Cytometry Data
Background: In a high throughput setting, effective flow cytometry data analysis depends heavily on proper data preprocessing. While usual preprocessing steps of quality assessmen...
Greg Finak, Juan-Manuel Perez, Andrew Weng, Raphae...
JCC
2011
133views more  JCC 2011»
13 years 3 months ago
MIBPB: A software package for electrostatic analysis
: The Poisson–Boltzmann equation (PBE) is an established model for the electrostatic analysis of biomolecules. The development of advanced computational techniques for the soluti...
Duan Chen, Zhan Chen, Changjun Chen, Weihua Geng, ...
BMCBI
2011
13 years 3 months ago
SNPPicker: High quality tag SNP selection across multiple populations
Background: Linkage Disequilibrium (LD) bin-tagging algorithms identify a reduced set of tag SNPs that can capture the genetic variation in a population without genotyping every s...
Hugues Sicotte, David N. Rider, Gregory A. Poland,...
SIGIR
2011
ACM
12 years 11 months ago
Why searchers switch: understanding and predicting engine switching rationales
Search engine switching is the voluntary transition between Web search engines. Engine switching can occur for a number of reasons, including user dissatisfaction with search resu...
Qi Guo, Ryen W. White, Yunqiao Zhang, Blake Anders...
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