Background: The genomes of prokaryotes and lower eukaryotes display a very strong 11 bp periodic bias in the distribution of their nucleotides. This bias is present throughout a g...
Background: The majority of residues in protein structures are involved in the formation of helices and -strands. These distinctive secondary structure patterns can be used to rep...
Indraneel Majumdar, S. Sri Krishna, Nick V. Grishi...
Background: Cis-regulatory modules are combinations of regulatory elements occurring in close proximity to each other that control the spatial and temporal expression of genes. Th...
Voichita D. Marinescu, Isaac S. Kohane, Alberto Ri...
Background: The availability of the human genome sequence as well as the large number of physically accessible oligonucleotides, cDNA, and BAC clones across the entire genome has ...
Background: A number of algorithms for steady state analysis of metabolic networks have been developed over the years. Of these, Elementary Mode Analysis (EMA) has proven especial...
Roland Schwarz, Patrick Musch, Axel von Kamp, Bern...