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BMCBI
2005
127views more  BMCBI 2005»
13 years 7 months ago
Genomes are covered with ubiquitous 11 bp periodic patterns, the "class A flexible patterns"
Background: The genomes of prokaryotes and lower eukaryotes display a very strong 11 bp periodic bias in the distribution of their nucleotides. This bias is present throughout a g...
Etienne Larsabal, Antoine Danchin
BMCBI
2005
101views more  BMCBI 2005»
13 years 7 months ago
PALSSE: A program to delineate linear secondary structural elements from protein structures
Background: The majority of residues in protein structures are involved in the formation of helices and -strands. These distinctive secondary structure patterns can be used to rep...
Indraneel Majumdar, S. Sri Krishna, Nick V. Grishi...
BMCBI
2005
169views more  BMCBI 2005»
13 years 7 months ago
MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes
Background: Cis-regulatory modules are combinations of regulatory elements occurring in close proximity to each other that control the spatial and temporal expression of genes. Th...
Voichita D. Marinescu, Isaac S. Kohane, Alberto Ri...
BMCBI
2005
180views more  BMCBI 2005»
13 years 7 months ago
arrayCGHbase: an analysis platform for comparative genomic hybridization microarrays
Background: The availability of the human genome sequence as well as the large number of physically accessible oligonucleotides, cDNA, and BAC clones across the entire genome has ...
Björn Menten, Filip Pattyn, Katleen De Preter...
BMCBI
2005
94views more  BMCBI 2005»
13 years 7 months ago
YANA - a software tool for analyzing flux modes, gene-expression and enzyme activities
Background: A number of algorithms for steady state analysis of metabolic networks have been developed over the years. Of these, Elementary Mode Analysis (EMA) has proven especial...
Roland Schwarz, Patrick Musch, Axel von Kamp, Bern...