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BMCBI
2006
13 years 8 months ago
2006
Background: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, cal...
BMCBI
2006
13 years 8 months ago
2006
Background: Stochastic simulation has become a useful tool to both study natural biological systems and design new synthetic ones. By capturing the intrinsic molecular fluctuation...
BMCBI
2006
13 years 8 months ago
2006
Background: Sequence comparison is one of the most prominent tools in biological research, and is instrumental in studying gene function and evolution. The rapid development of hi...
BMCBI
2006
13 years 8 months ago
2006
Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
BMCBI
2006
13 years 8 months ago
2006
Background: There is an ever increasing rate of data made available on genetic variation, transcriptomes and proteomes. Similarly, a growing variety of bioinformatic programs are ...