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BMCBI
2010
13 years 7 months ago
2010
Background: Codon bias is believed to play an important role in the control of gene expression. In Escherichia coli, some rare codons, which can limit the expression level of exog...
BMCBI
2010
13 years 7 months ago
2010
Background: A large effort to discover microRNAs (miRNAs) has been under way. Currently miRBase is their primary repository, providing annotations of primary sequences, precursors...
BMCBI
2010
13 years 7 months ago
2010
Background: Human genome contains millions of common single nucleotide polymorphisms (SNPs) and these SNPs play an important role in understanding the association between genetic ...
BMCBI
2010
13 years 7 months ago
2010
Background: High-throughput DNA methylation arrays are likely to accelerate the pace of methylation biomarker discovery for a wide variety of diseases. A potential problem with a ...
BMCBI
2010
13 years 7 months ago
2010
Background: Knowledge of transcription factor-DNA binding patterns is crucial for understanding gene transcription. Numerous DNA-binding proteins are annotated as transcription fa...