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BMCBI
2005
13 years 7 months ago
2005
Background: Detection of Loss of Heterozygosity (LOH) is one of the most common molecular applications in the study of human diseases, in particular cancer. The technique is commo...
BMCBI
2005
13 years 7 months ago
2005
Background: Currently real time PCR is the most precise method by which to measure gene expression. The method generates a large amount of raw numerical data and processing may no...
BMCBI
2005
13 years 7 months ago
2005
Background: The large gap between the number of protein sequences in databases and the number of functionally characterized proteins calls for the development of a fast computatio...
BMCBI
2005
13 years 7 months ago
2005
Background: Protein sequence alignments have become indispensable for virtually any evolutionary, structural or functional study involving proteins. Modern sequence search and com...
BMCBI
2005
13 years 7 months ago
2005
Background: Post-translational modification by Small Ubiquitin-like Modifiers (SUMO) has been implicated in protein targeting, in the maintenance of genomic integrity and in trans...