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    BMCBI
    2010
    179views more  BMCBI 2010»
    A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
    13 years 11 months ago
    A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
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    Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
    Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...
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    BMCBI
    2010
    100views more  BMCBI 2010»
    Partitioning of copy-number genotypes in pedigrees
    13 years 11 months ago
    Partitioning of copy-number genotypes in pedigrees
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    Background: Copy number variations (CNVs) and polymorphisms (CNPs) have only recently gained the genetic community's attention. Conservative estimates have shown that CNVs an...
    Louis-Philippe Lemieux Perreault, Gregor U. Andelf...
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    BMCBI
    2010
    127views more  BMCBI 2010»
    Computational prediction of type III secreted proteins from gram-negative bacteria
    13 years 11 months ago
    Computational prediction of type III secreted proteins from gram-negative bacteria
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    Background: Type III secretion system (T3SS) is a specialized protein delivery system in gramnegative bacteria that injects proteins (called effectors) directly into the eukaryoti...
    Yang Yang, Jiayuan Zhao, Robyn L. Morgan, Wenbo Ma...
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    BMCBI
    2008
    90views more  BMCBI 2008»
    Genome-scale study of the importance of binding site context for transcription factor binding and gene regulation
    13 years 11 months ago
    Genome-scale study of the importance of binding site context for transcription factor binding and gene regulation
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    Background: The rate of mRNA transcription is controlled by transcription factors that bind to specific DNA motifs in promoter regions upstream of protein coding genes. Recent res...
    Jakub Orzechowski Westholm, Feifei Xu, Hans Ronne,...
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    BMCBI
    2008
    95views more  BMCBI 2008»
    Methodology capture: discriminating between the "best" and the rest of community practice
    13 years 11 months ago
    Methodology capture: discriminating between the "best" and the rest of community practice
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    Background: The methodologies we use both enable and help define our research. However, as experimental complexity has increased the choice of appropriate methodologies has become...
    James M. Eales, John W. Pinney, Robert D. Stevens,...
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