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» Dimensions of Component Based Development
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BMCBI
2008
175views more  BMCBI 2008»
13 years 8 months ago
Comprehensive inventory of protein complexes in the Protein Data Bank from consistent classification of interfaces
Background: Protein-protein interactions are ubiquitous and essential for all cellular processes. High-resolution X-ray crystallographic structures of protein complexes can reveal...
Andrew J. Bordner, Andrey A. Gorin
BMCBI
2008
159views more  BMCBI 2008»
13 years 8 months ago
Estimation and testing for the effect of a genetic pathway on a disease outcome using logistic kernel machine regression via log
Background: Growing interest on biological pathways has called for new statistical methods for modeling and testing a genetic pathway effect on a health outcome. The fact that gen...
Dawei Liu, Debashis Ghosh, Xihong Lin
BMCBI
2008
110views more  BMCBI 2008»
13 years 8 months ago
Enhancing the prediction of protein pairings between interacting families using orthology information
Background: It has repeatedly been shown that interacting protein families tend to have similar phylogenetic trees. These similarities can be used to predicting the mapping betwee...
José M. G. Izarzugaza, David de Juan, Carle...
CSDA
2008
128views more  CSDA 2008»
13 years 7 months ago
Classification tree analysis using TARGET
Tree models are valuable tools for predictive modeling and data mining. Traditional tree-growing methodologies such as CART are known to suffer from problems including greediness,...
J. Brian Gray, Guangzhe Fan
EM
2010
155views Management» more  EM 2010»
13 years 7 months ago
Hyperbolic Graphs of Small Complexity
In this paper we enumerate and classify the "simplest" pairs (M, G) where M is a closed orientable 3-manifold and G is a trivalent graph embedded in M. To enumerate the p...
Damian Heard, Craig Hodgson, Bruno Martelli, Carlo...