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BMCBI
2005
169views more  BMCBI 2005»
13 years 7 months ago
Genetic interaction motif finding by expectation maximization - a novel statistical model for inferring gene modules from synthe
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Yan Qi 0003, Ping Ye, Joel S. Bader
BMCBI
2004
177views more  BMCBI 2004»
13 years 7 months ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
JCNS
2011
87views more  JCNS 2011»
13 years 2 months ago
Information-geometric measure of 3-neuron firing patterns characterizes scale-dependence in cortical networks
To understand the functional connectivity of neural networks, it is important to develop simple and incisive descriptors of multineuronal firing patterns. Analysis at the pairwise...
Ifije E. Ohiorhenuan, Jonathan D. Victor
SDM
2009
SIAM
192views Data Mining» more  SDM 2009»
14 years 4 months ago
Mining Cohesive Patterns from Graphs with Feature Vectors.
The increasing availability of network data is creating a great potential for knowledge discovery from graph data. In many applications, feature vectors are given in addition to g...
Arash Rafiey, Flavia Moser, Martin Ester, Recep Co...
BRAIN
2010
Springer
13 years 6 months ago
Sparse Regression Models of Pain Perception
Discovering brain mechanisms underlying pain perception remains a challenging neuroscientific problem with important practical applications, such as developing better treatments f...
Irina Rish, Guillermo A. Cecchi, Marwan N. Baliki,...