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BMCBI
2010
131views more  BMCBI 2010»
13 years 8 months ago
Prediction of epigenetically regulated genes in breast cancer cell lines
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
Leandro A. Loss, Anguraj Sadanandam, Steffen Durin...
BMCBI
2005
114views more  BMCBI 2005»
13 years 8 months ago
Signal transduction pathway profiling of individual tumor samples
Background: Signal transduction pathways convey information from the outside of the cell to transcription factors, which in turn regulate gene expression. Our objective is to anal...
Thomas Breslin, Morten Krogh, Carsten Peterson, Ca...
CORR
2008
Springer
152views Education» more  CORR 2008»
13 years 8 months ago
Characterizing User Mobility in Second Life
In this work we present a measurement study of user mobility in Second Life. We first discuss different techniques to collect user traces and then focus on results obtained using ...
Chi-Anh La, Pietro Michiardi
GECCO
2006
Springer
161views Optimization» more  GECCO 2006»
14 years 6 days ago
An empirical investigation of how and why neutrality affects evolutionary search
The effects of neutrality on evolutionary search have been considered in a number of interesting studies, the results of which, however, have been contradictory. Some researchers ...
Edgar Galván López, Riccardo Poli
WSC
2000
13 years 10 months ago
Mathematical programming models of discrete event system dynamics
Analytical models for the dynamics of some discrete event systems are introduced where the system trajectories are solutions to linear and mixed-integer programs. 1 BACKGROUND The...
Lee Schruben