Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...
We present a numerical approximation technique for the analysis of continuous-time Markov chains that describe networks of biochemical reactions and play an important role in the ...
Thomas A. Henzinger, Maria Mateescu, Linar Mikeev,...
Discrete Event Simulation (DES) has been used as a design and validation tool in various production and business applications. DES can also be utilized for analyzing the product-m...
Simulation has been used traditionally to solve other areas problems. Real time applications like videogames use typically a continuous simulation scheme. That way of operation ha...
With the availability of huge databases cataloguing the various molecular “parts” of complex biological systems, researchers from multiple disciplines have focused on developi...
Samik Ghosh, Preetam Ghosh, Kalyan Basu, Sajal K. ...