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» Discretization: An Enabling Technique
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BMCBI
2008
93views more  BMCBI 2008»
15 years 6 months ago
MPDA: Microarray pooled DNA analyzer
Background: Microarray-based pooled DNA experiments that combine the merits of DNA pooling and gene chip technology constitute a pivotal advance in biotechnology. This new techniq...
Hsin-Chou Yang, Mei-Chu Huang, Ling-Hui Li, Chien-...
BMCBI
2008
138views more  BMCBI 2008»
15 years 6 months ago
CASCADE: a novel quasi all paths-based network analysis algorithm for clustering biological interactions
Background: Quantitative characterization of the topological characteristics of protein-protein interaction (PPI) networks can enable the elucidation of biological functional modu...
Woochang Hwang, Young-Rae Cho, Aidong Zhang, Mural...
BMCBI
2008
145views more  BMCBI 2008»
15 years 6 months ago
Mapping gene expression quantitative trait loci by singular value decomposition and independent component analysis
Background: The combination of gene expression profiling with linkage analysis has become a powerful paradigm for mapping gene expression quantitative trait loci (eQTL). To date, ...
Shameek Biswas, John D. Storey, Joshua M. Akey
BMCBI
2008
128views more  BMCBI 2008»
15 years 6 months ago
An efficient visualization tool for the analysis of protein mutation matrices
Background: It is useful to develop a tool that would effectively describe protein mutation matrices specifically geared towards the identification of mutations that produce eithe...
Maria Pamela C. David, Carlo M. Lapid, Vincent Ric...
BMCBI
2008
185views more  BMCBI 2008»
15 years 6 months ago
Mining clinical relationships from patient narratives
Background: The Clinical E-Science Framework (CLEF) project has built a system to extract clinically significant information from the textual component of medical records in order...
Angus Roberts, Robert J. Gaizauskas, Mark Hepple, ...