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MICCAI
2010
Springer
13 years 5 months ago
Biomarkers for Identifying First-Episode Schizophrenia Patients Using Diffusion Weighted Imaging
Recent advances in diffusion weighted MR imaging (dMRI) has made it a tool of choice for investigating white matter abnormalities of the brain and central nervous system. In this w...
Yogesh Rathi, James G. Malcolm, Oleg V. Michailovi...
BMCBI
2006
172views more  BMCBI 2006»
13 years 7 months ago
Prediction of cis/trans isomerization in proteins using PSI-BLAST profiles and secondary structure information
Background: The majority of peptide bonds in proteins are found to occur in the trans conformation. However, for proline residues, a considerable fraction of Prolyl peptide bonds ...
Jiangning Song, Kevin Burrage, Zheng Yuan, Thomas ...
BMCBI
2010
120views more  BMCBI 2010»
13 years 7 months ago
KiDoQ: using docking based energy scores to develop ligand based model for predicting antibacterials
Background: Identification of novel drug targets and their inhibitors is a major challenge in the field of drug designing and development. Diaminopimelic acid (DAP) pathway is a u...
Aarti Garg, Rupinder Tewari, Gajendra P. S. Raghav...
BMCBI
2010
146views more  BMCBI 2010»
13 years 7 months ago
Nonnegative principal component analysis for mass spectral serum profiles and biomarker discovery
Background: As a novel cancer diagnostic paradigm, mass spectroscopic serum proteomic pattern diagnostics was reported superior to the conventional serologic cancer biomarkers. Ho...
Henry Han
BMCBI
2006
120views more  BMCBI 2006»
13 years 7 months ago
Optimizing amino acid substitution matrices with a local alignment kernel
Background: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, cal...
Hiroto Saigo, Jean-Philippe Vert, Tatsuya Akutsu