Background: The binding of regulatory proteins to their specific DNA targets determines the accurate expression of the neighboring genes. The in silico prediction of new binding s...
Background: Recognizing similarities and deriving relationships among protein molecules is a fundamental requirement in present-day biology. Similarities can be present at various...
Background: Alternative splicing is a major contributor to the diversity of eukaryotic transcriptomes and proteomes. Currently, large scale detection of alternative splicing using...
Rileen Sinha, Michael Hiller, Rainer Pudimat, Ulri...
Background: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of st...
Background: Few genetic factors predisposing to the sporadic form of amyotrophic lateral sclerosis (ALS) have been identified, but the pathology itself seems to be a true multifac...
Silvana Penco, Massimo Buscema, Maria Cristina Pat...