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ISMB
1996
13 years 9 months ago
A Knowledge-Based Method for Protein Structure Refinement and Prediction
The native conformation of a protein, in a given environment, is determined entirely by the various interatomic interactions dictated by the amino acid sequence (1-3). We describe...
Shankar Subramaniam, David K. Tcheng, James M. Fen...
BMCBI
2010
152views more  BMCBI 2010»
13 years 7 months ago
Apples and oranges: avoiding different priors in Bayesian DNA sequence analysis
Background: One of the challenges of bioinformatics remains the recognition of short signal sequences in genomic DNA such as donor or acceptor splice sites, splicing enhancers or ...
Jens Keilwagen, Jan Grau, Stefan Posch, Ivo Grosse
CVPR
2012
IEEE
11 years 10 months ago
A learning-based framework for depth ordering
Depth ordering is instrumental for understanding the 3D geometry of an image. We as humans are surprisingly good ordering even with abstract 2D line drawings. In this paper we pro...
Zhaoyin Jia, Andrew C. Gallagher, Yao-Jen Chang, T...
BMCBI
2010
128views more  BMCBI 2010»
13 years 7 months ago
Conserved residue clusters at protein-protein interfaces and their use in binding site identification
Background: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of st...
Mainak Guharoy, Pinak Chakrabarti
BMCBI
2006
165views more  BMCBI 2006»
13 years 7 months ago
Improved variance estimation of classification performance via reduction of bias caused by small sample size
Background: Supervised learning for classification of cancer employs a set of design examples to learn how to discriminate between tumors. In practice it is crucial to confirm tha...
Ulrika Wickenberg-Bolin, Hanna Göransson, M&a...