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BMCBI
2010
243views more  BMCBI 2010»
13 years 9 months ago
Comparative study of unsupervised dimension reduction techniques for the visualization of microarray gene expression data
Background: Visualization of DNA microarray data in two or three dimensional spaces is an important exploratory analysis step in order to detect quality issues or to generate new ...
Christoph Bartenhagen, Hans-Ulrich Klein, Christia...
BMCBI
2008
100views more  BMCBI 2008»
13 years 9 months ago
Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen p
Background: T-cell epitopes that promiscuously bind to multiple alleles of a human leukocyte antigen (HLA) supertype are prime targets for development of vaccines and immunotherap...
Guanglan Zhang, Asif M. Khan, Kellathur N. Sriniva...
DEBU
2008
186views more  DEBU 2008»
13 years 9 months ago
A Survey of Collaborative Recommendation and the Robustness of Model-Based Algorithms
The open nature of collaborative recommender systems allows attackers who inject biased profile data to have a significant impact on the recommendations produced. Standard memory-...
Jeff J. Sandvig, Bamshad Mobasher, Robin D. Burke
DKE
2008
79views more  DKE 2008»
13 years 9 months ago
Extracting k most important groups from data efficiently
We study an important data analysis operator, which extracts the k most important groups from data (i.e., the k groups with the highest aggregate values). In a data warehousing co...
Man Lung Yiu, Nikos Mamoulis, Vagelis Hristidis
BMCBI
2006
170views more  BMCBI 2006»
13 years 9 months ago
Biclustering of gene expression data by non-smooth non-negative matrix factorization
Background: The extended use of microarray technologies has enabled the generation and accumulation of gene expression datasets that contain expression levels of thousands of gene...
Pedro Carmona-Saez, Roberto D. Pascual-Marqui, Fra...