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» Disease Modeling Using Evolved Discriminate Function
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SMI
2008
IEEE
116views Image Analysis» more  SMI 2008»
14 years 4 months ago
Self-organizing primitives for automated shape composition
Motivated by the ability of living cells to form into specific shapes and structures, we present a new approach to shape modeling based on self-organizing primitives whose behavi...
Linge Bai, Manolya Eyiyurekli, David E. Breen
BMCBI
2010
141views more  BMCBI 2010»
13 years 10 months ago
BioPhysConnectoR: Connecting Sequence Information and Biophysical Models
Background: One of the most challenging aspects of biomolecular systems is the understanding of the coevolution in and among the molecule(s). A complete, theoretical picture of th...
Franziska Hoffgaard, Philipp Weil, Kay Hamacher
BIODATAMINING
2008
163views more  BIODATAMINING 2008»
13 years 10 months ago
Multivariate profiling of neurodegeneration-associated changes in a subcellular compartment of neurons via image processing
Background: Dysfunction in the endolysosome, a late endosomal to lysosomal degradative intracellular compartment, is an early hallmark of some neurodegenerative diseases, in parti...
Saravana K. Kumarasamy, Yunshi Wang, Vignesh Viswa...
BMCBI
2010
117views more  BMCBI 2010»
13 years 10 months ago
Properties and identification of antibiotic drug targets
Background: We analysed 48 non-redundant antibiotic target proteins from all bacteria, 22 antibiotic target proteins from E. coli only and 4243 non-drug targets from E. coli to id...
Tala Bakheet, Andrew J. Doig
TMI
2002
386views more  TMI 2002»
13 years 9 months ago
Tracking Leukocytes In Vivo with Shape and Size Constrained Active Contours
Inflammatory disease is initiated by leukocytes (white blood cells) rolling along the inner surface lining of small blood vessels called postcapillary venules. Studying the number ...
Nilanjan Ray, Scott T. Acton, Klaus Ley