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BMCBI
2004
13 years 10 months ago
2004
Background: Microarray studies in cancer compare expression levels between two or more sample groups on thousands of genes. Data analysis follows a population-level approach (e.g....
BMCBI
2004
13 years 10 months ago
2004
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...
BMCBI
2004
13 years 10 months ago
2004
Background: The rapidly increasing number of completely sequenced genomes led to the establishment of the COG-database which, based on sequence homologies, assigns similar protein...
BMCBI
2004
13 years 10 months ago
2004
Background: Recent genomic and bioinformatic advances have motivated the development of numerous network models intending to describe graphs of biological, technological, and soci...
BMCBI
2004
13 years 10 months ago
2004
Background: Researchers who use MEDLINE for text mining, information extraction, or natural language processing may benefit from having a copy of MEDLINE that they can manage loca...