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ALMOB
2008
85views more  ALMOB 2008»
13 years 10 months ago
Noisy: Identification of problematic columns in multiple sequence alignments
Motivation: Sequence-based methods for phylogenetic reconstruction from (nucleic acid) sequence data are notoriously plagued by two effects: homoplasies and alignment errors. Larg...
Andreas W. M. Dress, Christoph Flamm, Guido Fritzs...
BIOINFORMATICS
2010
127views more  BIOINFORMATICS 2010»
13 years 10 months ago
Analyzing taxonomic classification using extensible Markov models
Motivation: As next generation sequencing is rapidly adding new genomes, their correct placement in the taxonomy needs verification. However, the current methods for confirming cl...
Rao M. Kotamarti, Michael Hahsler, Douglas Raiford...
BIODATAMINING
2008
117views more  BIODATAMINING 2008»
13 years 10 months ago
Search extension transforms Wiki into a relational system: A case for flavonoid metabolite database
Background: In computer science, database systems are based on the relational model founded by Edgar Codd in 1970. On the other hand, in the area of biology the word 'databas...
Masanori Arita, Kazuhiro Suwa
BIOINFORMATICS
2008
172views more  BIOINFORMATICS 2008»
13 years 10 months ago
Fitting a geometric graph to a protein-protein interaction network
Motivation: Finding a good network null model for protein-protein interaction (PPI) networks is a fundamental issue. Such a model would provide insights into the interplay between...
Desmond J. Higham, Marija Rasajski, Natasa Przulj
BMCBI
2010
135views more  BMCBI 2010»
13 years 10 months ago
Delineation of amplification, hybridization and location effects in microarray data yields better-quality normalization
Background: Oligonucleotide arrays have become one of the most widely used high-throughput tools in biology. Due to their sensitivity to experimental conditions, normalization is ...
Marc Hulsman, Anouk Mentink, Eugene P. van Someren...
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