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BMCBI
2006
130views more  BMCBI 2006»
13 years 7 months ago
Spatial normalization of array-CGH data
Background: Array-based comparative genomic hybridization (array-CGH) is a recently developed technique for analyzing changes in DNA copy number. As in all microarray analyses, no...
Pierre Neuvial, Philippe Hupé, Isabel Brito...
BMCBI
2005
92views more  BMCBI 2005»
13 years 7 months ago
Predicting functional sites with an automated algorithm suitable for heterogeneous datasets
Background: In a previous report (La et al., Proteins, 2005), we have demonstrated that the identification of phylogenetic motifs, protein sequence fragments conserving the overal...
David La, Dennis R. Livesay
BMCBI
2005
103views more  BMCBI 2005»
13 years 7 months ago
Quadratic regression analysis for gene discovery and pattern recognition for non-cyclic short time-course microarray experiments
Background: Cluster analyses are used to analyze microarray time-course data for gene discovery and pattern recognition. However, in general, these methods do not take advantage o...
Hua Liu, Sergey Tarima, Aaron S. Borders, Thomas V...
BMCBI
2005
251views more  BMCBI 2005»
13 years 7 months ago
Contextual weighting for Support Vector Machines in literature mining: an application to gene versus protein name disambiguation
Background: The ability to distinguish between genes and proteins is essential for understanding biological text. Support Vector Machines (SVMs) have been proven to be very effici...
Tapio Pahikkala, Filip Ginter, Jorma Boberg, Jouni...
BMCBI
2004
166views more  BMCBI 2004»
13 years 7 months ago
Gene prediction using the Self-Organizing Map: automatic generation of multiple gene models
Background: Many current gene prediction methods use only one model to represent proteincoding regions in a genome, and so are less likely to predict the location of genes that ha...
Shaun Mahony, James O. McInerney, Terry J. Smith, ...