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141
Voted
BMCBI
2010
130views more  BMCBI 2010»
15 years 3 months ago
The behaviour of random forest permutation-based variable importance measures under predictor correlation
Background: Random forests (RF) have been increasingly used in applications such as genome-wide association and microarray studies where predictor correlation is frequently observ...
Kristin K. Nicodemus, James D. Malley, Carolin Str...
137
Voted
BMCBI
2010
176views more  BMCBI 2010»
15 years 3 months ago
Bayesian statistical modelling of human protein interaction network incorporating protein disorder information
Background: We present a statistical method of analysis of biological networks based on the exponential random graph model, namely p2-model, as opposed to previous descriptive app...
Svetlana Bulashevska, Alla Bulashevska, Roland Eil...
136
Voted
BMCBI
2010
190views more  BMCBI 2010»
15 years 3 months ago
A parallel and incremental algorithm for efficient unique signature discovery on DNA databases
Background: DNA signatures are distinct short nucleotide sequences that provide valuable information that is used for various purposes, such as the design of Polymerase Chain Reac...
Hsiao Ping Lee, Tzu-Fang Sheu, Chuan Yi Tang
142
Voted
BMCBI
2010
154views more  BMCBI 2010»
15 years 3 months ago
EnvMine: A text-mining system for the automatic extraction of contextual information
Background: For ecological studies, it is crucial to count on adequate descriptions of the environments and samples being studied. Such a description must be done in terms of thei...
Javier Tamames, Victor de Lorenzo
128
Voted
BMCBI
2010
116views more  BMCBI 2010»
15 years 3 months ago
A hybrid approach to protein folding problem integrating constraint programming with local search
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
Abu Zafer M. Dayem Ullah, Kathleen Steinhöfel