Cluster analysis is a common approach to pattern discovery in spatial databases. While many clustering techniques have been developed, it is still challenging to discover implicit...
Background: Clustering the ESTs from a large dataset representing a single species is a convenient starting point for a number of investigations into gene discovery, genome evolut...
We present an algorithm, Hierarchical ISOmetric SelfOrganizing Map (H-ISOSOM), for a concise, organized manifold representation of complex, non-linear, large scale, high-dimension...
Manifold learning methods are promising data analysis tools. However, if we locate a new test sample on the manifold, we have to find its embedding by making use of the learned e...
Many bioinformatics problems can implicitly depend on estimating large-scale covariance matrix. The traditional approaches tend to give rise to high variance and low accuracy esti...