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BMCBI
2006
167views more  BMCBI 2006»
15 years 2 months ago
GOurmet: A tool for quantitative comparison and visualization of gene expression profiles based on gene ontology (GO) distributi
Background: The ever-expanding population of gene expression profiles (EPs) from specified cells and tissues under a variety of experimental conditions is an important but difficu...
Jason M. Doherty, Lynn K. Carmichael, Jason C. Mil...
138
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BMCBI
2006
100views more  BMCBI 2006»
15 years 2 months ago
Design of microarray probes for virus identification and detection of emerging viruses at the genus level
Background: Most virus detection methods are geared towards the detection of specific single viruses or just a few known targets, and lack the capability to uncover the novel viru...
Cheng-Chung Chou, Te-Tsui Lee, Chun-Houh Chen, Hsi...
106
Voted
BMCBI
2006
171views more  BMCBI 2006»
15 years 2 months ago
The effect of oligonucleotide microarray data pre-processing on the analysis of patient-cohort studies
Background: Intensity values measured by Affymetrix microarrays have to be both normalized, to be able to compare different microarrays by removing non-biological variation, and s...
Roel G. W. Verhaak, Frank J. T. Staal, Peter J. M....
BMCBI
2006
202views more  BMCBI 2006»
15 years 2 months ago
Integrated biclustering of heterogeneous genome-wide datasets for the inference of global regulatory networks
Background: The learning of global genetic regulatory networks from expression data is a severely under-constrained problem that is aided by reducing the dimensionality of the sea...
David J. Reiss, Nitin S. Baliga, Richard Bonneau
144
Voted
BMCBI
2006
113views more  BMCBI 2006»
15 years 2 months ago
QualitySNP: a pipeline for detecting single nucleotide polymorphisms and insertions/deletions in EST data from diploid and polyp
Background: Single nucleotide polymorphisms (SNPs) are important tools in studying complex genetic traits and genome evolution. Computational strategies for SNP discovery make use...
Jifeng Tang, Ben Vosman, Roeland E. Voorrips, C. G...