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BIODATAMINING
2008
178views more  BIODATAMINING 2008»
13 years 10 months ago
Clustering-based approaches to SAGE data mining
Serial analysis of gene expression (SAGE) is one of the most powerful tools for global gene expression profiling. It has led to several biological discoveries and biomedical appli...
Haiying Wang, Huiru Zheng, Francisco Azuaje
BMCBI
2010
157views more  BMCBI 2010»
13 years 10 months ago
SeqTrim: a high-throughput pipeline for pre-processing any type of sequence read
Background: High-throughput automated sequencing has enabled an exponential growth rate of sequencing data. This requires increasing sequence quality and reliability in order to a...
Juan Falgueras, Antonio J. Lara, Noé Fern&a...
BMCBI
2010
103views more  BMCBI 2010»
13 years 10 months ago
Predicting the protein-protein interactions using primary structures with predicted protein surface
Background: Many biological functions involve various protein-protein interactions (PPIs). Elucidating such interactions is crucial for understanding general principles of cellula...
Darby Tien-Hao Chang, Yu-Tang Syu, Po-Chang Lin
BMCBI
2010
110views more  BMCBI 2010»
13 years 10 months ago
MultiRTA: A simple yet reliable method for predicting peptide binding affinities for multiple class II MHC allotypes
Background: The binding of peptide fragments of antigens to class II MHC is a crucial step in initiating a helper T cell immune response. The identification of such peptide epitop...
Andrew J. Bordner, Hans D. Mittelmann
BMCBI
2010
98views more  BMCBI 2010»
13 years 10 months ago
A semi-nonparametric mixture model for selecting functionally consistent proteins
Background: High-throughput technologies have led to a new era of proteomics. Although protein microarray experiments are becoming more common place there are a variety of experim...
Lianbo Yu, R. W. Doerge