117 search results - page 17 / 24 » Effect of Background Correction on Cancer Classification wit... |
BMCBI
2008
13 years 7 months ago
2008
Background: Analysis of gene expression data for tumor classification is an important application of bioinformatics methods. But it is hard to analyse gene expression data from DN...
BMCBI
2008
13 years 7 months ago
2008
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
BMCBI
2005
13 years 7 months ago
2005
Background: Chromosomal copy number changes (aneuploidies) play a key role in cancer progression and molecular evolution. These copy number changes can be studied using microarray...
BMCBI
2005
13 years 7 months ago
2005
Background: Human heart failure is a complex disease that manifests from multiple genetic and environmental factors. Although ischemic and non-ischemic heart disease present clini...
BMCBI
2004
13 years 7 months ago
2004
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...