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NIPS
2003
13 years 8 months ago
ICA-based Clustering of Genes from Microarray Expression Data
We propose an unsupervised methodology using independent component analysis (ICA) to cluster genes from DNA microarray data. Based on an ICA mixture model of genomic expression pa...
Su-In Lee, Serafim Batzoglou
BMCBI
2008
160views more  BMCBI 2008»
13 years 6 months ago
A comparison of four clustering methods for brain expression microarray data
Background: DNA microarrays, which determine the expression levels of tens of thousands of genes from a sample, are an important research tool. However, the volume of data they pr...
Alexander L. Richards, Peter Holmans, Michael C. O...
BMCBI
2006
155views more  BMCBI 2006»
13 years 6 months ago
AffyMiner: mining differentially expressed genes and biological knowledge in GeneChip microarray data
Background: DNA microarrays are a powerful tool for monitoring the expression of tens of thousands of genes simultaneously. With the advance of microarray technology, the challeng...
Guoqing Lu, The V. Nguyen, Yuannan Xia, Michael Fr...
BMCBI
2005
148views more  BMCBI 2005»
13 years 6 months ago
Nonparametric tests for differential gene expression and interaction effects in multi-factorial microarray experiments
Background: Numerous nonparametric approaches have been proposed in literature to detect differential gene expression in the setting of two user-defined groups. However, there is ...
Xin Gao, Peter X. K. Song
BMCBI
2010
214views more  BMCBI 2010»
13 years 6 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper