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BMCBI
2006
165views more  BMCBI 2006»
13 years 8 months ago
A stable gene selection in microarray data analysis
Background: Microarray data analysis is notorious for involving a huge number of genes compared to a relatively small number of samples. Gene selection is to detect the most signi...
Kun Yang, Zhipeng Cai, Jianzhong Li, Guohui Lin
BMCBI
2006
172views more  BMCBI 2006»
13 years 8 months ago
A novel scoring schema for peptide identification by searching protein sequence databases using tandem mass spectrometry data
Background: Tandem mass spectrometry (MS/MS) is a powerful tool for protein identification. Although great efforts have been made in scoring the correlation between tandem mass sp...
Zhuo Zhang, Shiwei Sun, Xiaopeng Zhu, Suhua Chang,...
BMCBI
2006
137views more  BMCBI 2006»
13 years 8 months ago
A classification-based framework for predicting and analyzing gene regulatory response
Background: We have recently introduced a predictive framework for studying gene transcriptional regulation in simpler organisms using a novel supervised learning algorithm called...
Anshul Kundaje, Manuel Middendorf, Mihir Shah, Chr...
BMCBI
2006
126views more  BMCBI 2006»
13 years 8 months ago
A Regression-based K nearest neighbor algorithm for gene function prediction from heterogeneous data
Background: As a variety of functional genomic and proteomic techniques become available, there is an increasing need for functional analysis methodologies that integrate heteroge...
Zizhen Yao, Walter L. Ruzzo
BMCBI
2006
141views more  BMCBI 2006»
13 years 8 months ago
Asymptotic behaviour and optimal word size for exact and approximate word matches between random sequences
Background: The number of k-words shared between two sequences is a simple and effcient alignment-free sequence comparison method. This statistic, D2, has been used for the cluste...
Sylvain Forêt, Miriam R. Kantorovitz, Conrad...