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BMCBI
2004
113views more  BMCBI 2004»
13 years 7 months ago
Influence of microarrays experiments missing values on the stability of gene groups by hierarchical clustering
Background: Microarray technologies produced large amount of data. The hierarchical clustering is commonly used to identify clusters of co-expressed genes. However, microarray dat...
Alexandre G. de Brevern, Serge A. Hazout, Alain Ma...
BMCBI
2004
114views more  BMCBI 2004»
13 years 7 months ago
Profiled support vector machines for antisense oligonucleotide efficacy prediction
Background: This paper presents the use of Support Vector Machines (SVMs) for prediction and analysis of antisense oligonucleotide (AO) efficacy. The collected database comprises ...
Gustavo Camps-Valls, Alistair M. Chalk, Antonio J....
BMCBI
2004
154views more  BMCBI 2004»
13 years 7 months ago
Computation of elementary modes: a unifying framework and the new binary approach
Background: Metabolic pathway analysis has been recognized as a central approach to the structural analysis of metabolic networks. The concept of elementary (flux) modes provides ...
Julien Gagneur, Steffen Klamt
BMCBI
2004
162views more  BMCBI 2004»
13 years 7 months ago
Identifying spatially similar gene expression patterns in early stage fruit fly embryo images: binary feature versus invariant m
Background: Modern developmental biology relies heavily on the analysis of embryonic gene expression patterns. Investigators manually inspect hundreds or thousands of expression p...
Rajalakshmi Gurunathan, Bernard Van Emden, Sethura...
BMCBI
2004
150views more  BMCBI 2004»
13 years 7 months ago
Rank Difference Analysis of Microarrays (RDAM), a novel approach to statistical analysis of microarray expression profiling data
Background: A key step in the analysis of microarray expression profiling data is the identification of genes that display statistically significant changes in expression signals ...
Dietmar E. Martin, Philippe Demougin, Michael N. H...