Intervals represent a fundamental data type for temporal, scientific, and spatial databases where time stamps and point data are extended to time spans and range data, respectively...
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
Dimension reduction is a critical data preprocessing step for many database and data mining applications, such as efficient storage and retrieval of high-dimensional data. In the ...
Jieping Ye, Qi Li, Hui Xiong, Haesun Park, Ravi Ja...
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
Maximum margin clustering (MMC) is a recent large margin unsupervised learning approach that has often outperformed conventional clustering methods. Computationally, it involves n...