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» Efficient Evaluation of Large Polynomials
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BMCBI
2010
90views more  BMCBI 2010»
13 years 7 months ago
Using caching and optimization techniques to improve performance of the Ensembl website
Background: The Ensembl web site has provided access to genomic information for almost 10 years. During this time the amount of data available through Ensembl has grown dramatical...
Anne Parker, Eugene Bragin, Simon Brent, Bethan Pr...
BMCBI
2010
139views more  BMCBI 2010»
13 years 7 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
BMCBI
2008
114views more  BMCBI 2008»
13 years 7 months ago
Testing the Coulomb/Accessible Surface Area solvent model for protein stability, ligand binding, and protein design
Background: Protein structure prediction and computational protein design require efficient yet sufficiently accurate descriptions of aqueous solvent. We continue to evaluate the ...
Marcel Schmidt am Busch, Anne Lopes, Najette Amara...
CN
2008
100views more  CN 2008»
13 years 7 months ago
Building resilient low-diameter peer-to-peer topologies
As more applications rely on underlying peer-to-peer topologies, the need for efficient and resilient infrastructure has become more pressing. A number of important classes of top...
Rita H. Wouhaybi, Andrew T. Campbell
BIOINFORMATICS
2006
106views more  BIOINFORMATICS 2006»
13 years 7 months ago
Identification of biochemical networks by S-tree based genetic programming
Motivation: Most previous approaches to model biochemical networks havefocusedeither on the characterization of a networkstructurewith a number of components or on the estimation ...
Dong-Yeon Cho, Kwang-Hyun Cho, Byoung-Tak Zhang