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BMCBI
2004
127views more  BMCBI 2004»
13 years 7 months ago
Optimized LOWESS normalization parameter selection for DNA microarray data
Background: Microarray data normalization is an important step for obtaining data that are reliable and usable for subsequent analysis. One of the most commonly utilized normaliza...
John A. Berger, Sampsa Hautaniemi, Anna-Kaarina J&...
BMCBI
2004
200views more  BMCBI 2004»
13 years 7 months ago
ABC: software for interactive browsing of genomic multiple sequence alignment data
Background: Alignment and comparison of related genome sequences is a powerful method to identify regions likely to contain functional elements. Such analyses are data intensive, ...
Gregory M. Cooper, Senthil A. G. Singaravelu, Aren...
BMCBI
2004
162views more  BMCBI 2004»
13 years 7 months ago
Identifying spatially similar gene expression patterns in early stage fruit fly embryo images: binary feature versus invariant m
Background: Modern developmental biology relies heavily on the analysis of embryonic gene expression patterns. Investigators manually inspect hundreds or thousands of expression p...
Rajalakshmi Gurunathan, Bernard Van Emden, Sethura...
BMCBI
2004
115views more  BMCBI 2004»
13 years 7 months ago
An SVD-based comparison of nine whole eukaryotic genomes supports a coelomate rather than ecdysozoan lineage
Background: Eukaryotic whole genome sequences are accumulating at an impressive rate. Effective methods for comparing multiple whole eukaryotic genomes on a large scale are needed...
Gary W. Stuart, Michael W. Berry
COMPLEXITY
2004
165views more  COMPLEXITY 2004»
13 years 7 months ago
Sex promotes gamete selection: A quantitative comparative study of features favoring the evolution of sex
: Explaining the maintenance of sexual reproduction remains one of the greatest challenges in biology. The theoretical oddity of sex is based on at least three advantages that asex...
Klaus Jaffe