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BMCBI
2010
179views more  BMCBI 2010»
13 years 10 months ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...
BMCBI
2010
122views more  BMCBI 2010»
13 years 10 months ago
Ovarian cancer classification based on dimensionality reduction for SELDI-TOF data
Background: Recent advances in proteomics technologies such as SELDI-TOF mass spectrometry has shown promise in the detection of early stage cancers. However, dimensionality reduc...
Kai-Lin Tang, Tong-Hua Li, Wen-Wei Xiong, Kai Chen
BMCBI
2010
136views more  BMCBI 2010»
13 years 10 months ago
SCPS: a fast implementation of a spectral method for detecting protein families on a genome-wide scale
Background: An important problem in genomics is the automatic inference of groups of homologous proteins from pairwise sequence similarities. Several approaches have been proposed...
Tamás Nepusz, Rajkumar Sasidharan, Alberto ...
BMCBI
2010
118views more  BMCBI 2010»
13 years 10 months ago
Artificial neural networks for the prediction of peptide drift time in ion mobility mass spectrometry
Background: There is an increasing usage of ion mobility-mass spectrometry (IMMS) in proteomics. IMMS combines the features of ion mobility spectrometry (IMS) and mass spectrometr...
Bing Wang, Steve Valentine, Manolo Plasencia, Srir...
BMCBI
2010
154views more  BMCBI 2010»
13 years 10 months ago
EnvMine: A text-mining system for the automatic extraction of contextual information
Background: For ecological studies, it is crucial to count on adequate descriptions of the environments and samples being studied. Such a description must be done in terms of thei...
Javier Tamames, Victor de Lorenzo