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BMCBI
2010
156views more  BMCBI 2010»
13 years 9 months ago
Mathematical model for empirically optimizing large scale production of soluble protein domains
Background: Efficient dissection of large proteins into their structural domains is critical for high throughput proteome analysis. So far, no study has focused on mathematically ...
Eisuke Chikayama, Atsushi Kurotani, Takanori Tanak...
BMCBI
2008
153views more  BMCBI 2008»
13 years 9 months ago
Estimating the size of the solution space of metabolic networks
Background: Cellular metabolism is one of the most investigated system of biological interactions. While the topological nature of individual reactions and pathways in the network...
Alfredo Braunstein, Roberto Mulet, Andrea Pagnani
BMCBI
2008
121views more  BMCBI 2008»
13 years 9 months ago
Stability of gene contributions and identification of outliers in multivariate analysis of microarray data
Background: Multivariate ordination methods are powerful tools for the exploration of complex data structures present in microarray data. These methods have several advantages com...
Florent Baty, Daniel Jaeger, Frank Preiswerk, Mart...
BMCBI
2008
208views more  BMCBI 2008»
13 years 9 months ago
GraphFind: enhancing graph searching by low support data mining techniques
Background: Biomedical and chemical databases are large and rapidly growing in size. Graphs naturally model such kinds of data. To fully exploit the wealth of information in these...
Alfredo Ferro, Rosalba Giugno, Misael Mongiov&igra...
COMPUTING
2008
174views more  COMPUTING 2008»
13 years 9 months ago
Multilevel algorithms for Rannacher-Turek finite element approximation of 3D elliptic problems
Generalizing the approach of a previous work [15] the authors present multilevel preconditioners for three-dimensional (3D) elliptic problems discretized by a family of Rannacher ...
Ivan Georgiev, Johannes Kraus, Svetozar Margenov