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BMCBI
2006
138views more  BMCBI 2006»
13 years 7 months ago
Determination of strongly overlapping signaling activity from microarray data
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Ghislain Bidaut, Karsten Suhre, Jean-Michel Claver...
BMCBI
2006
130views more  BMCBI 2006»
13 years 7 months ago
CARMA: A platform for analyzing microarray datasets that incorporate replicate measures
Background: The incorporation of statistical models that account for experimental variability provides a necessary framework for the interpretation of microarray data. A robust ex...
Kevin A. Greer, Matthew R. McReynolds, Heddwen L. ...
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
GOPET: A tool for automated predictions of Gene Ontology terms
Background: Vast progress in sequencing projects has called for annotation on a large scale. A Number of methods have been developed to address this challenging task. These method...
Arunachalam Vinayagam, Coral del Val, Falk Schuber...
BMCBI
2006
127views more  BMCBI 2006»
13 years 7 months ago
Improvement in the Reproducibility and Accuracy of DNA Microarray Quantification by Optimizing Hybridization Conditions
Background: DNA microarrays, which have been increasingly used to monitor mRNA transcripts at a global level, can provide detailed insight into cellular processes involved in resp...
Tao Han, Cathy D. Melvin, Leming M. Shi, William S...
BMCBI
2006
129views more  BMCBI 2006»
13 years 7 months ago
EGenBio: A Data Management System for Evolutionary Genomics and Biodiversity
Background: Evolutionary genomics requires management and filtering of large numbers of diverse genomic sequences for accurate analysis and inference on evolutionary processes of ...
Laila A. Nahum, Matthew T. Reynolds, Zhengyuan O. ...
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