Background: Codon substitution probabilities are used in many types of molecular evolution studies such as determining Ka/Ks ratios, creating ancestral DNA sequences or aligning c...
Adrian Schneider, Gina Cannarozzi, Gaston H. Gonne...
We develop here an analytical evolution model based on a trinucleotide mutation matrix 64 × 64 with nine substitution parameters associated with the three types of substitutions ...
Background: Codon substitution constitutes a fundamental process in molecular biology that has been studied extensively. However, prior studies rely on various assumptions, e.g. r...
Thispaperintroducesa methodfor identifyingempirically conservedaminoacid substitution groups.In contrast with existing approachesthat viewaminoacid substitution as a pairwisepheno...
Abstract. We present a formal analysis of amino acid replacement during mRNA translation. Building on an abstract stochastic model of arrival of tRNAs and their processing at the r...
Dragan Bosnacki, Huub M. M. ten Eikelder, M. N. St...