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GCB
2000
Springer
137views Biometrics» more  GCB 2000»
13 years 10 months ago
Detecting Sporadic Recombination in DNA Alignments with Hidden Markov Models
Conventional phylogenetic tree estimation methods assume that all sites in a DNA multiple alignment have the same evolutionary history. This assumption is violated in data sets fro...
Dirk Husmeier, Frank Wright
BMCBI
2008
103views more  BMCBI 2008»
13 years 7 months ago
Parameter estimation for robust HMM analysis of ChIP-chip data
Background: Tiling arrays are an important tool for the study of transcriptional activity, proteinDNA interactions and chromatin structure on a genome-wide scale at high resolutio...
Peter Humburg, David Bulger, Glenn Stone
BMCBI
2010
113views more  BMCBI 2010»
13 years 7 months ago
Unifying generative and discriminative learning principles
Background: The recognition of functional binding sites in genomic DNA remains one of the fundamental challenges of genome research. During the last decades, a plethora of differe...
Jens Keilwagen, Jan Grau, Stefan Posch, Marc Stric...
CRV
2009
IEEE
237views Robotics» more  CRV 2009»
14 years 1 months ago
SEC: Stochastic Ensemble Consensus Approach to Unsupervised SAR Sea-Ice Segmentation
The use of synthetic aperture radar (SAR) has become an integral part of sea-ice monitoring and analysis in the polar regions. An important task in sea-ice analysis is to segment ...
Alexander Wong, David A. Clausi, Paul W. Fieguth
BMCBI
2008
144views more  BMCBI 2008»
13 years 7 months ago
Local conservation scores without a priori assumptions on neutral substitution rates
Background: Comparative genomics aims to detect signals of evolutionary conservation as an indicator of functional constraint. Surprisingly, results of the ENCODE project revealed...
Janis Dingel, Pavol Hanus, Niccolò Leonardi...