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CORR
2004
Springer
168views Education» more  CORR 2004»
13 years 11 months ago
Estimating Genome Reversal Distance by Genetic Algorithm
Sorting by reversals is an important problem in inferring the evolutionary relationship between two genomes. The problem of sorting unsigned permutation has been proven to be NP-ha...
Andy Auyeung, Ajith Abraham
DAM
2008
116views more  DAM 2008»
13 years 11 months ago
Expected number of breakpoints after t random reversals in genomes with duplicate genes
In comparative genomics, one wishes to deduce the evolutionary distance between dierent species by studying their genomes. Using gene order information, we seek the number of time...
Niklas Eriksen
CIBCB
2005
IEEE
14 years 4 months ago
Heuristic Algorithm for Computing Reversal Distance with MultiGene Families via Binary Integer Programming
— Hannenhalli and Pevzner developed the first polynomial-time algorithm for the combinatorial problem of sorting of signed genomic data. Their algorithm solves the minimum numbe...
Jakkarin Suksawatchon, Chidchanok Lursinsap, Mikae...
STOC
1995
ACM
194views Algorithms» more  STOC 1995»
14 years 2 months ago
Transforming cabbage into turnip: polynomial algorithm for sorting signed permutations by reversals
Genomes frequently evolve by reversals ␳(i, j) that transform a gene order ␲1 . . . ␲i␲iϩ1 . . . ␲jϪ1␲j . . . ␲n into ␲1 . . . ␲i␲jϪ1 . . . ␲iϩ1␲j . . ....
Sridhar Hannenhalli, Pavel A. Pevzner
JDA
2007
156views more  JDA 2007»
13 years 11 months ago
A linear time algorithm for the inversion median problem in circular bacterial genomes
In the median problem, we are given a distance or dissimilarity measure d, three genomes G1, G2, and G3, and we want to find a genome G (a median) such that the sum 3 i=1 d(G, Gi...
Enno Ohlebusch, Mohamed Ibrahim Abouelhoda, Kathri...