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» Estimating dynamic models for gene regulation networks
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BIBE
2010
IEEE
135views Bioinformatics» more  BIBE 2010»
13 years 7 months ago
Finding Dynamic Modules of Biological Regulatory Networks
—Often groups of genes in regulatory networks, also called modules, work collaboratively on similar functions. Mathematically, the modules in a regulatory network has often been ...
Ferhat Ay, Thang N. Dinh, My T. Thai, Tamer Kahvec...
WABI
2009
Springer
124views Bioinformatics» more  WABI 2009»
14 years 2 months ago
Mimosa: Mixture Model of Co-expression to Detect Modulators of Regulatory Interaction
Background: Functionally related genes tend to be correlated in their expression patterns across multiple conditions and/or tissue-types. Thus co-expression networks are often use...
Matthew Hansen, Logan Everett, Larry Singh, Sridha...
JCB
2002
131views more  JCB 2002»
13 years 7 months ago
Modeling and Simulation of Genetic Regulatory Systems: A Literature Review
In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The reg...
Hidde de Jong
TSMC
2010
13 years 2 months ago
On Robust Stability of Stochastic Genetic Regulatory Networks With Time Delays: A Delay Fractioning Approach
Robust stability serves as an important regulation mechanism in system biology and synthetic biology. In this paper, the robust stability analysis problem is investigated for a cla...
Yao Wang, Zidong Wang, Jinling Liang
BMCBI
2010
97views more  BMCBI 2010»
13 years 7 months ago
Dual-functioning transcription factors in the developmental gene network of Drosophila melanogaster
Background: Quantitative models for transcriptional regulation have shown great promise for advancing our understanding of the biological mechanisms underlying gene regulation. Ho...
Denis C. Bauer, Fabian A. Buske, Timothy L. Bailey