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» Estimating dynamic models for gene regulation networks
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EJASP
2010
132views more  EJASP 2010»
13 years 2 months ago
Uncovering Transcriptional Regulatory Networks by Sparse Bayesian Factor Model
The problem of uncovering transcriptional regulation by transcription factors (TFs) based on microarray data is considered. A novel Bayesian sparse correlated rectified factor mod...
Jia Meng, Jianqiu Zhang, Yuan (Alan) Qi, Yidong Ch...
CMSB
2004
Springer
13 years 11 months ago
Residual Bootstrapping and Median Filtering for Robust Estimation of Gene Networks from Microarray Data
We propose a robust estimation method of gene networks based on microarray gene expression data. It is well-known that microarray data contain a large amount of noise and some outl...
Seiya Imoto, Tomoyuki Higuchi, SunYong Kim, Euna J...
IJCNN
2006
IEEE
14 years 1 months ago
Computational Neurogenetic Modeling: A Methodology to Study Gene Interactions Underlying Neural Oscillations
—We present new results from Computational Neurogenetic Modeling to aid discoveries of complex gene interactions underlying oscillations in neural systems. Interactions of genes ...
Lubica Benuskova, Simei Gomes Wysoski, Nikola K. K...
BMCBI
2005
122views more  BMCBI 2005»
13 years 7 months ago
A microarray data-based semi-kinetic method for predicting quantitative dynamics of genetic networks
Background: Elucidating the dynamic behaviour of genetic regulatory networks is one of the most significant challenges in systems biology. However, conventional quantitative predi...
Katsuyuki Yugi, Yoichi Nakayama, Shigen Kojima, To...
BICOB
2010
Springer
14 years 9 days ago
Biological Relevance Detection via Network Dynamic Analysis
Most existing approaches for gene selection are based on evaluating the statistical relevance. However, there are remarkable discrepancies between statistical relevance and biolog...
Zheng Zhao, Huan Liu, Jiangxin Wang, Yung Chang