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» Estimating dynamic models for gene regulation networks
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BMCBI
2010
144views more  BMCBI 2010»
13 years 7 months ago
Super-sparse principal component analyses for high-throughput genomic data
Background: Principal component analysis (PCA) has gained popularity as a method for the analysis of highdimensional genomic data. However, it is often difficult to interpret the ...
Donghwan Lee, Woojoo Lee, Youngjo Lee, Yudi Pawita...
RECOMB
2005
Springer
14 years 7 months ago
An Interaction-Dependent Model for Transcription Factor Binding
Transcriptional regulation is accomplished by several transcription factor proteins that bind to specific DNA elements in the relative vicinity of the gene, and interact with each ...
Li-San Wang, Shane T. Jensen, Sridhar Hannenhalli
BMCBI
2008
146views more  BMCBI 2008»
13 years 7 months ago
A phase synchronization clustering algorithm for identifying interesting groups of genes from cell cycle expression data
Background: The previous studies of genome-wide expression patterns show that a certain percentage of genes are cell cycle regulated. The expression data has been analyzed in a nu...
Chang Sik Kim, Cheol Soo Bae, Hong Joon Tcha
BMCBI
2010
109views more  BMCBI 2010»
13 years 7 months ago
Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression
Background: In the last decade, biochemical studies have revealed that epigenetic modifications including histone modifications, histone variants and DNA methylation form a comple...
Xiaojiang Xu, Stephen Hoang, Marty W. Mayo, Stefan...
CORR
2008
Springer
115views Education» more  CORR 2008»
13 years 7 months ago
Positive circuits and maximal number of fixed points in discrete dynamical systems
We consider a product X of n finite intervals of integers, a map F from X to itself, the asynchronous state transition graph (F) on X that Thomas proposed as a model for the dynam...
Adrien Richard