Sciweavers

1098 search results - page 143 / 220
» Evaluating Statistical Power Optimization
Sort
View
BMCBI
2008
159views more  BMCBI 2008»
13 years 9 months ago
Estimation and testing for the effect of a genetic pathway on a disease outcome using logistic kernel machine regression via log
Background: Growing interest on biological pathways has called for new statistical methods for modeling and testing a genetic pathway effect on a health outcome. The fact that gen...
Dawei Liu, Debashis Ghosh, Xihong Lin
BMCBI
2008
121views more  BMCBI 2008»
13 years 9 months ago
Stability of gene contributions and identification of outliers in multivariate analysis of microarray data
Background: Multivariate ordination methods are powerful tools for the exploration of complex data structures present in microarray data. These methods have several advantages com...
Florent Baty, Daniel Jaeger, Frank Preiswerk, Mart...
BMCBI
2011
13 years 1 months ago
Robust joint analysis allowing for model uncertainty in two-stage genetic association studies
Background: The cost efficient two-stage design is often used in genome-wide association studies (GWASs) in searching for genetic loci underlying the susceptibility for complex di...
Dongdong Pan, Qizhai Li, Ningning Jiang, Aiyi Liu,...
BMCBI
2011
13 years 1 months ago
Estimation of allele frequency and association mapping using next-generation sequencing data
Background: Estimation of allele frequency is of fundamental importance in population genetic analyses and in association mapping. In most studies using next-generation sequencing...
Su Yeon Kim, Kirk E. Lohmueller, Anders Albrechtse...
MANSCI
2007
90views more  MANSCI 2007»
13 years 9 months ago
Selecting a Selection Procedure
Selection procedures are used in a variety of applications to select the best of a finite set of alternatives. ‘Best’ is defined with respect to the largest mean, but the me...
Jürgen Branke, Stephen E. Chick, Christian Sc...