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BMCBI
2005
122views more  BMCBI 2005»
13 years 8 months ago
FACT - a framework for the functional interpretation of high-throughput experiments
Background: Interpreting the results of high-throughput experiments, such as those obtained from DNA-microarrays, is an often time-consuming task due to the high number of data-po...
Felix Kokocinski, Nicolas Delhomme, Gunnar Wrobel,...
BMCBI
2005
89views more  BMCBI 2005»
13 years 8 months ago
An empirical analysis of training protocols for probabilistic gene finders
Background: Generalized hidden Markov models (GHMMs) appear to be approaching acceptance as a de facto standard for state-of-the-art ab initio gene finding, as evidenced by the re...
William H. Majoros, Steven Salzberg
JCB
2007
144views more  JCB 2007»
13 years 8 months ago
Statistical Estimation of Statistical Mechanical Models: Helix-Coil Theory and Peptide Helicity Prediction
Analysis of biopolymer sequences and structures generally adopts one of two approaches: use of detailed biophysical theoretical models of the system with experimentally-determined...
Scott C. Schmidler, Joseph E. Lucas, Terrence G. O...
BMCBI
2005
189views more  BMCBI 2005»
13 years 8 months ago
A sentence sliding window approach to extract protein annotations from biomedical articles
Background: Within the emerging field of text mining and statistical natural language processing (NLP) applied to biomedical articles, a broad variety of techniques have been deve...
Martin Krallinger, Maria Padron, Alfonso Valencia
BMCBI
2005
131views more  BMCBI 2005»
13 years 8 months ago
Regularized Least Squares Cancer Classifiers from DNA microarray data
Background: The advent of the technology of DNA microarrays constitutes an epochal change in the classification and discovery of different types of cancer because the information ...
Nicola Ancona, Rosalia Maglietta, Annarita D'Addab...
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