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BMCBI
2006
123views more  BMCBI 2006»
13 years 7 months ago
How to decide? Different methods of calculating gene expression from short oligonucleotide array data will give different result
Background: Short oligonucleotide arrays for transcript profiling have been available for several years. Generally, raw data from these arrays are analysed with the aid of the Mic...
Frank F. Millenaar, John Okyere, Sean T. May, Mart...
BIBM
2008
IEEE
108views Bioinformatics» more  BIBM 2008»
14 years 1 months ago
Systematic Evaluation of Scaling Methods for Gene Expression Data
Even after an experimentally prepared gene expression data set has been pre-processed to account for variations in the microarray technology, there may be inconsistencies between ...
Gaurav Pandey, Lakshmi Naarayanan Ramakrishnan, Mi...
BMCBI
2008
96views more  BMCBI 2008»
13 years 7 months ago
Use of normalization methods for analysis of microarrays containing a high degree of gene effects
Background: High-throughput microarrays are widely used to study gene expression across tissues and developmental stages. Analysis of gene expression data is challenging in these ...
Terri T. Ni, William J. Lemon, Yu Shyr, Tao P. Zho...
BMCBI
2008
87views more  BMCBI 2008»
13 years 7 months ago
Global rank-invariant set normalization (GRSN) to reduce systematic distortions in microarray data
Background: Microarray technology has become very popular for globally evaluating gene expression in biological samples. However, non-linear variation associated with the technolo...
Carl R. Pelz, Molly Kulesz-Martin, Grover Bagby, R...
BMCBI
2005
135views more  BMCBI 2005»
13 years 7 months ago
A robust two-way semi-linear model for normalization of cDNA microarray data
Background: Normalization is a basic step in microarray data analysis. A proper normalization procedure ensures that the intensity ratios provide meaningful measures of relative e...
Deli Wang, Jian Huang, Hehuang Xie, Liliana Manzel...