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GI
2009
Springer
14 years 4 days ago
Massively-Parallel Simulation of Biochemical Systems
: Understanding biological evolution prompts for a detailed understanding of the realized phenotype. Biochemical and gene regulatory dynamics are a cornerstone for the physiology o...
Jens Ackermann, Paul Baecher, Thorsten Franzel, Mi...
RECOMB
2003
Springer
14 years 7 months ago
Designing seeds for similarity search in genomic DNA
Large-scale comparison of genomic DNA is of fundamental importance in annotating functional elements of genomes. To perform large comparisons efficiently, BLAST (Methods: Companio...
Jeremy Buhler, Uri Keich, Yanni Sun
WSC
2000
13 years 8 months ago
Analyzing transformation-based simulation metamodels
We present a technique for analyzing a simulation metamodel that has been constructed using a variancestabilizing transformation. To compute a valid confidence interval for the ex...
Maria de los A. Irizarry, Michael E. Kuhl, Emily K...
ESCIENCE
2006
IEEE
14 years 1 months ago
A Middleware Framework for Maximum Likelihood Evaluation over Dynamic Grids
We have designed a maximum likelihood fitter using the actor model to distribute the computation over a heterogeneous network. The prototype implementation uses the SALSA program...
Wei-Jen Wang, Kaoutar El Maghraoui, John Cummings,...
ISMB
2000
13 years 8 months ago
Analysis of Gene Expression Microarrays for Phenotype Classification
Several microarray technologies that monitor the level of expression of a large number of genes have recently emerged. Given DNA-microarray data for a set of cells characterized b...
Andrea Califano, Gustavo Stolovitzky, Yuhai Tu