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BMCBI
2008
133views more  BMCBI 2008»
13 years 6 months ago
CORE_TF: a user-friendly interface to identify evolutionary conserved transcription factor binding sites in sets of co-regulated
Background: The identification of transcription factor binding sites is difficult since they are only a small number of nucleotides in size, resulting in large numbers of false po...
Matthew S. Hestand, Michiel van Galen, Michel P. V...
BMCBI
2006
72views more  BMCBI 2006»
13 years 6 months ago
Selecting effective siRNA sequences by using radial basis function network and decision tree learning
Background: Although short interfering RNA (siRNA) has been widely used for studying gene functions in mammalian cells, its gene silencing efficacy varies markedly and there are o...
Shigeru Takasaki, Yoshihiro Kawamura, Akihiko Kona...
TCBB
2011
13 years 1 months ago
Learning Genetic Regulatory Network Connectivity from Time Series Data
Recent experimental advances facilitate the collection of time series data that indicate which genes in a cell are expressed. This paper proposes an efficient method to generate th...
Nathan A. Barker, Chris J. Myers, Hiroyuki Kuwahar...
BMCBI
2008
117views more  BMCBI 2008»
13 years 6 months ago
New resampling method for evaluating stability of clusters
Background: Hierarchical clustering is a widely applied tool in the analysis of microarray gene expression data. The assessment of cluster stability is a major challenge in cluste...
Irina Gana Dresen, Tanja Boes, Johannes Hüsin...
BMCBI
2008
101views more  BMCBI 2008»
13 years 6 months ago
Term-tissue specific models for prediction of gene ontology biological processes using transcriptional profiles of aging in dros
Background: Predictive classification on the base of gene expression profiles appeared recently as an attractive strategy for identifying the biological functions of genes. Gene O...
Wensheng Zhang, Sige Zou, Jiuzhou Song