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» Evolution of Biological Complexity
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WSC
2004
13 years 11 months ago
Using Simulated Data in Support of Research on Regression Analysis
Using simulated data to develop and study diagnostic tools for data analysis is very beneficial. The user can gain insight about what happens when assumptions are violated since t...
Christopher Michael Hill, Linda C. Malone
BMCBI
2010
155views more  BMCBI 2010»
13 years 10 months ago
FunctSNP: an R package to link SNPs to functional knowledge and dbAutoMaker: a suite of Perl scripts to build SNP databases
Background: Whole genome association studies using highly dense single nucleotide polymorphisms (SNPs) are a set of methods to identify DNA markers associated with variation in a ...
Stephen J. Goodswen, Cedric Gondro, Nathan S. Wats...
BMCBI
2010
82views more  BMCBI 2010»
13 years 10 months ago
Genome-wide estimation of firing efficiencies of origins of DNA replication from time-course copy number variation data
Background: DNA replication is a fundamental biological process during S phase of cell division. It is initiated from several hundreds of origins along whole chromosome with diffe...
Huaien Luo, Juntao Li, Majid Eshaghi, Jianhua Liu,...
BMCBI
2010
136views more  BMCBI 2010»
13 years 10 months ago
The IronChip evaluation package: a package of perl modules for robust analysis of custom microarrays
Background: Gene expression studies greatly contribute to our understanding of complex relationships in gene regulatory networks. However, the complexity of array design, producti...
Yevhen Vainshtein, Mayka Sanchez, Alvis Brazma, Ma...
BMCBI
2010
189views more  BMCBI 2010»
13 years 10 months ago
Efficient parallel and out of core algorithms for constructing large bi-directed de Bruijn graphs
Background: Assembling genomic sequences from a set of overlapping reads is one of the most fundamental problems in computational biology. Algorithms addressing the assembly probl...
Vamsi Kundeti, Sanguthevar Rajasekaran, Hieu Dinh,...