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BMCBI
2004
146views more  BMCBI 2004»
13 years 7 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker
GECCO
2003
Springer
167views Optimization» more  GECCO 2003»
14 years 20 days ago
Dimensionality Reduction via Genetic Value Clustering
Abstract. Feature extraction based on evolutionary search offers new possibilities for improving classification accuracy and reducing measurement complexity in many data mining and...
Alexander P. Topchy, William F. Punch
BMCBI
2010
138views more  BMCBI 2010»
13 years 7 months ago
UFFizi: a generic platform for ranking informative features
Background: Feature selection is an important pre-processing task in the analysis of complex data. Selecting an appropriate subset of features can improve classification or cluste...
Assaf Gottlieb, Roy Varshavsky, Michal Linial, Dav...
BMCBI
2010
115views more  BMCBI 2010»
13 years 7 months ago
Assessment and optimisation of normalisation methods for dual-colour antibody microarrays
Background: Recent advances in antibody microarray technology have made it possible to measure the expression of hundreds of proteins simultaneously in a competitive dual-colour a...
Martin Sill, Christoph Schroder, Jörg D. Hohe...
GPEM
2007
119views more  GPEM 2007»
13 years 7 months ago
Genomic mining for complex disease traits with "random chemistry"
Our rapidly growing knowledge regarding genetic variation in the human genome offers great potential for understanding the genetic etiology of disease. This, in turn, could revolut...
Margaret J. Eppstein, Joshua L. Payne, Bill C. Whi...